1887

PGD and Embryo Selection

Report from an International Conference on Preimplantation Genetic Diagnosis and Embryo Selection

image of PGD and Embryo Selection

The prenatal screening technologies are there and will be refined and used. However, prospective parents should be given a broad picture, including information from families with similarly impaired children and from disabled adults, and then be supported in their own choice. Different parents will then make different choices. Dóra S. Bjarnason, in ”Is life worth living if you have a disability?” ”The best way to have talented children is still to choose a talented spouse. Parents usually only wish that their children are healthy. And if they are not, they accept them anyway.” Outi Hovatta, in ”The new reproductive biology medical and technical possibilities vs. ethical and legal concerns” ”In the future, stem cell lines may be created from an HLA-identical embryo as identified by PGD. This would be an alternative for parents with a sick child without taking any risks associated with the creative of a potential donor child, and it may work much faster and thus increase the chance of benefit to the sick child” Gisela Dahlquist, in ”The child’s perspective and the parents’ who should decide?” ”There seems to be a common perception about which foetal or embryo condition could justify selection. The regulation will point at severe disorders, however, without indicating specifically which disorders could be considered sufficiently severe.” Mette Hartlev, in ”Legislation and regulations in the Nordic countries. Is there a Nordic dimension?” ”Personally I hold the view that well-founded doubt about the rightness of our moral deliberations, practices and visions is always better than unjustified confidence and conviction, even when we strive to decipher the moral status of unborn babies and supernumerary fertilised eggs. Consequently, I feel it is justified to remain in doubt about the exact nature of their moral status.” Jan Helge Solbakk, in ”On the moral status of unborn babies and supernumerary fertilised eggs” ”In developing countries, particularly in an Islamic context where there is a high premium placed on couples having at least one male offspring, the availability of pgd for non-medical reasons does have a positive effect.” Zaid Kilani, in ”Preimplantation Genetic Diagnosis for Elective Sex Selection: Individual Needs in Developing Countries, Financial, Social, Cultural and Religious Aspects”

English

.

Genetic diagnostics – what can it predict?

When we are discussing a sensitive and pioneering subject such as preimplantation genetic diagnostics, it is good to know for every contributor about his or her background, biases, and point of view. Mine is that of an active scientist trying to identify genes that are important in disease pathogenesis. I believe that susceptibility genes are important for improved diagnostics of diseases and for designing new pharmaceutical therapies. But I also believe that all the evidence so far shows that susceptibility genes will not be useful population screening targets and they are too imprecise for predicting disease with any useful accuracy. I shall review here some evidence that makes me believe that this is a fair statement for the time being, and perhaps for the foreseeable future.

English

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error