Endocrine Disrupters – Combination effects

image of Endocrine Disrupters – Combination effects

During the 2010 Danish Presidency of the Nordic Council of Ministers environment and health was a prioritized subject. The aim was enhanced Nordic information exchange. To support this aim a number of Nordic workshops were held to strengthen the capacity building and discuss future regulatory aspects in the area of endocrine disruptors, combination effects, and soft regulatory measures and effective risk communication. One of the workshops held in November focused on combination effects, with a special focus on endocrine disruptors. This report describes the workshop presentations, the ensuing discussions, and the outcome.




Exposure to a multi-component mixture of chemicals is part of everyday life and may affect both human health and the environment. Over the past 10–15 years the focus on the seriousness of the effects of exposure to such mixtures has increased. During recent years, the concern about combination effects of chemicals and especially endocrine disruptors has been further increased due to new scientific knowledge of “combination effects”. Several studies have shown that exposure to a combination of endocrine disrupting substances causes serious adverse effects at doses that, for the individual substance, do not lead to a significant effect.


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